• This topic is empty.
Viewing 2 posts - 1 through 2 (of 2 total)
  • Author
  • #4075

    SOPHiA GENETICS Partners to Provide COVID-19 Test
    The data-driven medicine leader is extending its partnership with Paragon Genomics to provide an NGS-based genomic testing solution for healthcare institutions worldwide. More Information

    Katie KingKatie King

    Experts are saying 1 in 3 COVID-19 infected patients are getting a false negative result with current testing methods (see article from the wall street journal: https://www.wsj.com/articles/questions-about-accuracy-of-coronavirus-tests-sow-worry-11585836001). In the landscape of containment, this is a scary statistic. With the next generation of testing, we hope to change these figures radically. SOPHiA is meeting with Senator Bennet on Monday to discuss our vision.

    SOPHiA GENETICS has partnered with Paragon genomics to provide a SARS-CoV-2 NGS panel to sequence the whole genome of the virus with 99% coverage. The assay is sensitive down to one copy per reaction for degraded or limited sample input, which can be from swabs, washes, aspirates, etc. This means greater sensitivity and fewer false negatives. The data will then be available for analysis in your own bioinformatics or via a SOPHiA report and will allow for surveillance of mutations across time and geographies. This assay provides a quick and extremely sensitive presence/absence test AND provides the whole sequence for in-depth research and surveillance.

    More details:
    Enrichment method: Multiplex PCR
    Platform: Illumina
    Reference Genome: NC_045512.2
    Number of Amplicons: 343
    Number of Primer Pools: 2
    Input of RNA Requirement: Approximately 50ng purified total RNA
    Assay Time: 5.5 hours
    Hands on Time: Less than 1 hour
    Design Coverage: 99.7% complete coverage, except 92bp at the ends of the genome

    The panel is available for shipment today and can be utilized immediately with electrophoresis for quick positive/negative results. NGS analysis via SOPHiA report will be available in approximately 3 weeks for further analysis of the entire viral genome.

    Please contact me if you would like to learn more.

    Katie King

Viewing 2 posts - 1 through 2 (of 2 total)
  • You must be logged in to reply to this topic.