b'We can attract an incredible medtech andfor people with low blood flow and dark skin life sciences workforce, and were one flightpigmentation. Medtronics Nellcor pulse away from anywhere in the United States,oximetry performs better for those patients. Chan says.A recent industry independent study from the Medtronic continues to partner with ColoradoUCSF hypoxia lab evaluated the performance life sciences companies to expand its tech- and accuracy of the Nellcor device and found nologies. It has a strategic partnership withthat it works better to level the playing field BioIntelliSense, a Golden-based continuousfor all patients.health monitoring and clinical intelligenceMedtronic has invested $2.3 billion in research company. Medtronics Acute Care & Monitoringand development in just the past year and business has exclusive rights to distributeis continuing to expand its R&D presence BioIntelliSenses BioButton, wearable forin Colorado and across the globe, with more continuous patient monitoring.than 11,000 scientists and engineers aroundsignificant investments in Colorado. Its The BioButton is a game changer for enablingthe world working to improve patient lives.Boulder-basedNucleicAcidsSolutions patients to leave the hospital, stay connectedAnd after five decades in Colorado, theDivision (NASD) built a 150,000-square-foot to caregivers, and alert them remotely ifcompany remains deeply committed to thiscomplex manufacturing building in Frederick theyre at risk of declining, says Chan. It allowscommunity, says Chan. in 2016, and it broke ground in February on hospitals, facing nursing shortages, to auto- Agilent Expands $750 Milliona 200,000-square-foot expansion. matically monitor patients vital signs and take proative clinical action if necessary. Manufacturing Operation All told, the company will put more than $750 in Frederick million into the campus. Weld County and the If you cant catch (decline) early, then theseTown of Frederick have been instrumental in patients will come back to the hospital andAgilent Technologies was born when Hewlett- helping us, as well as the state, says Brian thats a significant problem for the patientsPackard spun off its measurements divisionCarothers, Agilent Vice President & General themselves but also for payers and hospitals,in 1999. The new company would go on toManager, NASD.says Chan.be the largest IPO in Silicon Valley history andThe NASD division employs 450 people in The acute patient monitoring business teamto develop cutting-edge lab instruments toBoulder and Frederick and manufactures is also working with regulators, researchers,measure, analyze, and understand the worldtherapeutic nucleic acids, short DNA and RNA and clinicians, developing a new kind of pulsedown to the molecular level. molecules that serve as the active pharma-oximeter, because some of the existing tech- While Agilent is headquartered in Santaceutical ingredient for innovative biopharma nology on the market has shown limitationsClara, California, the company has madedrugs targeting diseases like cancer and heart disease. Clients include Alnylam and Lilly.Connected in Colorado: MedtronicsCarothers credits much of the growth to Acute Care & Monitoring business hasthe strong scientific community in Boulder exclusive rights to distribute Golden-based BioIntelliSenses BioButton. around oligonucleotide drug substances. Much of the evolution around the technology to manufacture oligonucleotide and short-chain materials came out of research by renowned University of Colorado biochemistry professor Marvin Caruthers (no relation). In the last few decades, it has led to startup spinoffs and a strong community of skilled scientists. Boulder-based Dicerna, now part of Novo Nordisk, manufactures this same type of material.A lot of the science is coming straight out of Boulder, says Agilents Carothers. The community of scientists, the people that truly understood this, has really grown over the years.8 BIOSCIENCE COLORADO 2024-2025'