b'KBI Biopharma Elevatestimelines and cost are reduced compared withKBI Biopharma operates six facilities Microbial Expressioncommon E. coli strains.worldwide, including two Colorado sites: a microbial facility in Boulder and Manufacturingand an analytical site in Louisville.We are raising the bar on microbial expression With unwavering dedication to efficiently man- and manufacturing, Stiff says. We represent ufacture high-performing therapies for patientswhere innovation meets impact.facing cancer, autoimmune diseases, or rareThe benefit expands to patients worldwide diseases, KBI Biopharma is a global contractas KBIs Boulder facility has made over 300 development and manufacturing organizationproduct batches at scale since the companys (CDMO) located at Flatiron Park.inception, supported over 20 Phase 1 to KBI, which operates multiple state-of-the-artPhase 3 clinical trials, and provided valuable facilities worldwide, established its microbialanalytical support.process development and manufacturingThe Boulder site is housed in five buildings operations in Boulder in 2014. Fast forwardspanning over 100,000 square feet in Flatiron more than a decade, and its Boulder operationPark, a hub of the states life sciences community. has grown from 90 to 400 employees, achievedIn addition to community-building at Flatiron recognition as a Center of Excellence, and isPark, Stiff has forged connections beyond her reimagining what can be done with microbes.normal manufacturing sphere by attending KBI has developed its own cell line, the PUREcoliCBSA events where she has gotten to know cell line, a proprietary, high-producing E. coli cellentrepreneurs,start-upcompanies,and line. Julie Stiff, Senior Vice President and Sitemedical device organizations.I so appreciateHead in Boulder, says that advances in genetic engineering, analytics, and strain screeningIts unique in Colorado because I have thebringing all of life chance to connect with people I would not rub have led to the development of this optimalelbows with naturally, says Stiff, a Coloradosciences together so therapeutic protein factory.native and graduate of CU Boulder. I so Stiff explains that PUREcoli superchargesappreciate CBSA bringing all of life scienceswe can help each other.bioprocessing by enhancing both efficiencytogether so we can help each other, and it and effectiveness. By providing higher titersbroadens my level of understanding of ourJULIE STIFF SENIOR VICE PRESIDENT & SITE HEAD (concentration) and higher purity from the start,potential clients. KBI BIOPHARMATHE TOUR ROUTE DAY ONEFitzsimons InnovationTerumo Blood andUmoja Biopharma, Community, Aurora Cell Technologies,LouisvilleLakewoodForesight Diagnostics, Colorado HealthMedtronic,Boulder& Tech Centers,LafayetteGreenwood Village28 BIOSCIENCE COLORADO 2025-2026'